Journal of Liver Cancer

Dongil Choi

3 Articles

Technical Advances in Radiofrequency Ablation of Hepatocellular Carcinoma: Dongil Choi, Hyunchul Rhim, Min Woo Lee; Journal of the Korean Liver Cancer Study Group. 2012;12(1):14-15. Published online February 28, 2012

Abstract PDF: Lots of recent technical advances in radiofrequency ablation (RFA) of hepatocellular carcinoma (HCC) have introduced. First, contrast-enhanced ultrasound can help to detect the index tumors, residual tumor, and local recurrence. After contrast-enhanced ultrasound for subtle small tumors, we can perform RFA with high confidence. The use of artificial ascites in RFA is a simple and useful technique to minimize collateral thermal injury and to improve the sonic window. Fusion imaging between US and CT or MR during RFA is useful since US can provide real-time imaging and CT or MR provides high quality images with good contrast and spatial resolution. RFA can be performed with fluoroscopy guidance to lipiodol retention tumors.

Recent CT for Liver Disease: Dongil Choi; Journal of the Korean Liver Cancer Study Group. 2011;11(1):23-25. Published online February 28, 2011

Abstract PDF: The recent advance in CT is the multidetector (MD) CT scanner. MDCT increases scan coverage, and can take shorter scan time, thinner sections and longer scan range. Double arterial phase imaging could show the high sensitivity of in hepatic tumor detection. CT angiography by using MDCT is useful in a detailed assessment of hepatic arterial anatomy using a three-dimensional dataset. Dual-energy CT was more recently introduced and popularized. Dual-source CT uses two energies, 140 and 80 kVp. This technique can measure chemical composition by dual-energy index. Dual-energy CT provides the ability for CT to differentiate between different materials at imaging. The latest technologic advancements in MDCT and availability of commercial software allow perfusion CT to offer a variety of clinical and research applications. Perfusion CT imaging can be used for the characterization and treatment monitoring of hepatic malignancies.

Clonorchis sinensis and Biliary Stones as Etiological Factors of Cholangiocarcinoma: Dongil Choi, Jae Hoon Lim; Journal of the Korean Liver Cancer Study Group. 2010;10(1):22-28. Published online June 30, 2010

Abstract PDF: C. sinensis induces adenomatous hyperplasia of the epithelium of the bile ducts, and the epithelium of the bile duct persistently exposed to biochemically altered bile may undergo the sequence, hyperplasia-metaplaisa-dysplasia-carcinoma. Cholangiocarcinomas were developed in most hamsters treated with an N-nitroso compound and then infected with C. sinensis. In the patients with intrahepatic duct stones, bile usually infected with bacteria. Mechanical stimuli due to stones, long-lasting bile stasis, and bacterial infection are considered to be the other significant causative factors in cholangiocarcinogenesis. Radiological examinations are essential in the diagnosis and treatment of biliary tree diseases including clonorchiasis, biliary stone disease, and cholangiocarcinoma. As both C. sinensis and intrahepatic duct stones are common, radiological and clinical findings should be attentively investigated for the possible presence of cholangiocarcinoma in patients with clonorchiasis or intrahepatic duct stones.